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Why the measurement method is so important when determining the values

Why the measurement method is so important when determining the values

Vitamin D is the only vitamin that the body With the help of the sun can produce yourself. Above all in winter If the solar intensity in this country is too low in order to absorb enough vitamin D – at least one would have to stay in the sun for hours and only a few do that at the temperatures.

According to the Robert Koch Institute (Rki) still don’t have to be automatic even in winter Take tablets – provided that Vitamin D memory in the body is sufficient. Although this statement is also heavily discussed in science, because some experts advocate taking vitamin D all year round. But how is the vitamin D level actually measured?

Important information in advance:

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  • The vitamin D level is measured using blood values. A preliminary stage of the active form, the 25-hydroxy vitamin d.
  • The measurement method is relevant for the assessment of the result. A reference range should therefore always be specified for the method.
  • Depending on the laboratory, vitamin D values ​​are specified in both NMOL/L and NG/ML (µg/l). You have a conversion factor of 2.496. There is less than 12 ng/ml Vitamin D deficiency before, the same only applies from 30 if the value is specified in NMOL/L.

Measure vitamin D levels: blood values ​​are important

In order to have the vitamin D level determined, a doctor must be consulted. The values ​​are determined by blood samples in the laboratory. As the RKI explains, the vitamin D level is determined by 25 hydroxy vitamin D, a preliminary stage of the active vitamin D in the body. It is most stable and is therefore best suited to determine the vitamin D value. Nevertheless, there are strong fluctuations. According to the Federal Ministry of Food and Agriculture, there are various measurement methods that can provide different results.

Both over and underestimations of the values ​​are possible. According to the ministry, the measurement method should therefore be taken into account when assessing the results. According to the RKI, a standardization of the methods has been advanced in the USA since 2010, and the RKI has subsequently standardized its procedures based on vitamin D.

Nevertheless, the methods in Germany are still not uniform and the differences in the results can be German Pharmacist Zeitung (DAZ) up to 38 percent. Since reference proceedings are sometimes expensive, immunological methods are often used in Germany. These are according to the Daz But often prone to interference.

Vitamin D mirror: Why isn’t the active shape measured?

Loud German pharmacist newspaper the most biologically active form of vitamin D only has a low half -life in the blood – only six to eight hours. That is not enough to measure the mirror in the laboratory. This is the reason why so -called precursors of the vitamin are used to determine the mirror. 25-hydroxy vitamin D, 25-oh-vit for short. D, according to the DAZ, « occurs in about 1000 times higher concentration in the blood than the active form ». The half -life is even three to four weeks, so the measurement is much more reliable.

After measuring: Why will the vitamin D level be specified in two units?

Depending on the laboratory, the values ​​are given in NMOL/L or in NG/ML (µg/l). According to the Daz the use in Germany is relatively balanced, but NMOL/L and NG/ML in the west is probably more often specified in the east. While a vitamin D level of 30 NMOL/L already represents an undersupply, the value in the NG/ml unit would be sufficient. Therefore, pay attention to the units when classifying your vitamin D level.

Measure and assess vitamin D levels-that’s how it works

A Optimal vitamin D value is 30 to 50 ng/ml or 75 to 125 NMOL/L. A value below 20 ng/ml can already affect bone health, especially in children. Here is the overview:

25 (oh) D in NMOL/L 25 (oh) D in NG/ml Evaluation
Vitamin D deficiency
30 bis 12 to Suboptimal care/vitamin D deficiency
50 to 20 bis Lower normal range; adequate supply as far as bone health is concerned
75 to 30 bis Optimal vitamin D value
≥125 ≥50 Possible oversupply, with potential consequences for health

Source: RKI, laboratory Enders

When should you have your vitamin D level determined?

Since vitamin D is very important for the body, everyone should keep an eye on their vitamin D level. Because even if you are often in the sun, you can develop a deficiency through various factors. For example blocked Sunscreen The formation of vitamin D. How much vitamin D a day is also very individual.

Risk groups in particular should have their vitamin D level measured regularly. According to the RKI, this includes:

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  • People who rarely stay outside. Only a small part of the daily requirement is covered with nutrition. The rest comes over the sun’s rays.
  • People who cover themselves for religious or cultural reasons. To produce sufficient vitamin D, about a quarter of the body should be uncovered.
  • People with darker skin types. Because your skin is more pigmented, more UV light is intercepted-it takes more intensive or longer sunlight to form sufficient vitamin D. In Germany, this UV exposure is often not sufficient even in summer.
  • People who suffer from chronic diseases of the gastrointestinal tract, the liver or kidney.
  • People who take certain medication, such as antiepileptics or cytostatics.

With certain symptoms, it can also be worthwhile to have the vitamin D level measured:

By the way: the word « Side effect » is for vitamin D Strictly speaking. Vitamin D is not the same as vitamin D. There are different shapesthat also work differently in the body.



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