This is how high the normal value in the blood should be

Vitamin B12 belongs to the group of B-vitamine And is chemically very complex, including a relatively large molecule. Although vitamin B12 to the water -soluble vitamins heard, it can be saved by the body. It consists of various chemical compounds that are summarized under the term cobalamins and have a characteristic red color.

Vitamin B12 is essential for the human body because it plays a key role in numerous biological processes. How high is the normal value in the blood?

Vitamin B12 in the blood: This is how the normal value is composed

Like any vitamin, vitamin B12 also has different shapes. There are different shapes in the meat than in dairy products. As the practicing internist and metabolic expert Helena Orfanos-Boeckel writes in her book « nutrient therapy », only methylcobalamine and adenosylcobalamine in the body can be converted into an active form. Both do not work in the body in the same places.

In order to test the supply of the body with vitamin B12, the concentration in the blood serum is tested. The value is not always meaningful, since vitamin B12 is also measured, which is not available for the body, as the association for promoting holistic health vitaminb12.de writes. Nevertheless, other auxiliary markers can serve to better assess the serum levels. The overall vitamin B12 and Holotranscobalamin (Holo-TC) serve as status markers. Other metabolic products serve as functional markers. Here is the overview:

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• Serum vitamin B12-Status marker: Vitamin B12 in the blood serum is made up of active forms that the body can use and inactive forms. Around 10 – 30 percent of serum levels are composed of the active form Holo -TC.
• Holotranscobalamin (Holo -TC) – Status marker: Holotranscobalamine is the active vitamin B12. According to the medical blade, it is considered the earliest marker for one Vitamin B12 deficiency. Lower values ​​of Holotranscobalamin are already displayed in the blood before there are clinical symptoms.
  
• Methylmalonic acid – Function marker – is also a functional marker for the content of vitamin B12. It is abbreviated to MMA. With an empty vitamin B12 memory, the values ​​in the blood rise.
• Homocysteine ​​- function marker – is an amino acid in the blood that is formed in the metabolism, but is also broken down thanks to vitamin B12 and folic acid. An increased value is considered a risk factor for cardiovascular diseases and can indicate a vitamin B12 deficiency.

Vitamin B12: Normal value and reference values ​​at an overview

Vitamin B12 is water -soluble and overdose is relatively rare. According to Helena Orfanos-Boeckel, it is normal if the vitamin B12 values ​​in the blood are increased after oral intake or injection. « This is not a harmful overdose. On the contrary, this is proof of successful treatment, » writes the doctor. In the long term, the values ​​should level off. In her guide, she specifies these target and reference values ​​ »nutrients – the practical guide »:

Vitamin B12 in serum:

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• Reference area: 200 – 2000 pg/ml
• Target value:> 1000 pg/ml

In the long term, conservation B12 serum mirror range from 700 to 900 special per milliliters (PG/ml).

Holotranscobalamin:

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• Reference range:> 37.5 – 150 PMOL/L
• Target value:> 100 pmol/l

Homocysteine:

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• Reference range:
• Target value: 7 µmol/

The values ​​of methylmalonic acid must be interpreted together with the creatinine ink concentration in the blood. According to the association for the promotion of holistic health, values ​​of 1.8 to 2.2 milligrams MMA per gram of creatinine can indicate a vitamin B12 deficiency. A lot of increased values ​​of 5 milligrams indicate a strong deficiency. Helena Orfanos-Boeckel rarely uses the methylmalonic acid value in the blood to diagnose a vitamin B12 deficiency, as she writes in her guide.

Vitamin B12 value: What is the supply in Germany?

According to the national consumption study II, only eight percent of men and 26 percent of women do not achieve daily intake of vitamin B12. As the German Nutrition Society writes, this is not to be equated with an undersupply. Unfortunately, the data is not up to date: they were collected between 2005 and 2007. The national consumption study III is currently underway, which is to be completed according to FISA 2025.

As early as 2008, the Ärzteblatt wrote in an article that a vitamin B12 deficiency was widespread and internist Helena Orfanos-Boeckel also wrote in her guide: « The lack in Germany is enormous. » The risk groups include vegans. Vitamin B12, which – in contrast to other vitamin B12 forms – can also be processed by the body is only contained in animal products. The need can increase in chronic diseases, in old age and stress. With good laboratory diagnostics, it can be found whether vitamin B12 therapy is necessary or sensible.