They gave the child experimental treatment. Repeated inflammation of the kidneys resolved transplantation
4. June 2025 at 16:57
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Slovaks are signed under a unique study.
BRATISLAVA. Doctor Barbora Piteková from the National Institute of Children’s Diseases, along with the international team of experts, signed under unique case studypublished in the prestigious Pediatric Nephrology magazine.
It describes the first known case when a fecal microbial transplant was used in a child with chronic urinary infections and kidney disease.
« The study discussed a ten -year patient with a posterior urethra valve (congenital developmental error system), which, as a result, suffered from repeated renal inflammation. Despite various urological surgery and long -term repeated administration of antibiotics, kidney inflammation still continued to stop and overcome a total of 28, » says Piteková.
Experts have decided on innovative treatment – a procedure that was used for the first time in Slovakia with such a disease.
Unique that worked
The boy already innate error at an early age, which prevented the proper outflow of urine, damaged the bladder and kidneys.
« Repeated inflammations are dangerous because they lead to kidney damage, which also happened in our patient. He had a chronic kidney disease at the penultimate stage. Therefore, he was considered the last option, namely the removal of the kidney, » tells the doctor about the case.
There were few options in standard treatment. Since the patient has found significant pathological changes in the intestinal microbiome (high representation of bacteria that cause kidney inflammation), doctors have opted for an unconventional but promising procedure: they gave him experimental treatment – faecal microbial transplantation.
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It is a transplant of intestinal microflora from a healthy donor.
« Treatment has led to adjusting the intestinal microbiome and stopping kidney inflammation. The patient is currently 20 months without inflammation and still has both kidneys. It is a breakthrough study that means a significant step in the management of pediatric patients with repeated kidney inflammation, » adds Piteková.
This was only the second case of using this method in a child with repeated urinary tract infections, it is unique in Slovakia.
How does faecal transplant work
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