Researchers identified genes responsible for obese
Researchers at Cambridge University have made an exciting discovery of Labrador retrievers When examining its genes, which can be associated with obesity not only dogs but also people. The research focuses on the DANNND1B gene that has a significant impact on dogs for obesityand plays a similar role in people. According to the researchers, this gene directly affects the control of the brain's energy balance, especially through the leptin-meranocortin system.
Four more gene were identified during the research, which can also be associated with the dogs By obesity, although their effects are smaller than DainD1B. These genes were mapped directly to human genes, which It opens up new opportunities to understand the genetic background of human obesity. Alyce McClellan, the leader of the research, emphasized that although these genes are not immediate targets for weight loss drugs, they play an important role in regulating appetite and body weight.
During the research it was observed that the for obesity Genetically prone dogs show more interest in food, which is a similar phenomenon in humans. Natalie Wallis, co -author of the research, said that the desire for dogs for food was separated from the extent to which farmers control the dogs' diet and exercise. This approach made it possible to better understand the relationship between genetic predisposition and environmental factors.
The results
The results of the research show that farmers who strictly control their dog's diets and exercise can prevent obesity even in dogs with high genetic risk. Similarly, people who have genetic predisposition to obesity can control their weight with a strict diet and exercise, although this requires greater effort.
Dr. Eleanor Raffan, leader of the research, pointed out that studying dogs helped to understand how the genetic risk of obesity influences eating habits. Dogs are genetically similar to people, which gives us the opportunity to better understand the genetic background of human obesity. During the research, pet owners were recruited and the dog's body fat was measured and DNA samples were collected for genetic analysis.
Research results provide a new perspective on obesity In understanding its genetic background, they highlight that, in addition to genetic predisposition, environmental factors also play a significant role in the development of obesity. According to the researchers, the hosts can distract their dogs from constant hunger by using different methods, such as the use of jigsaw puzzles or scattering the food in the garden.
Research results of a Science .
