First « very promising » steps towards a new therapeutic track – Liberation

It affects a little more than one in ten women of prosecutor, affects its fertility, can induce, among other things, metabolic disorders (diabetes, overweight, obesity), an excess of hair, increases the cardiovascular risk … and yet there is no treatment to attack the causes polycystic ovary syndrome (SOPK). Patients are only offered drugs, symptoms by symptom. But global research is activated.

In a study published this Friday, April 11 by the review Cell Metabolismresearchers from Inserm, CHU and the University of Lille sketch a new promising track: they have developed an antibody capable of restoring, mice with symptoms similar to disease, ovulation and a rate of androgens (male hormones) to normal. « These results show potential to treat fertility disorders », explain Release Paolo Giacobini, research director at Inserm who led this work.

The track is bounded with hopes: SOPK is the first cause of female infertility. The hormonal disruption which he induces leads to an overproduction of male hormones (especially testosterone), which cause a multiplication of follicles dan